SCHEMBL30629040

SCHEMBL30629040

O=Cc1ccc2c(c1)CCN2c1noc(C23CCC(CC2)CC3)n1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
ADRB2 P07550 3/20 0.35
ADRB1 P08588 3/20 0.35
HSD11B1 P28845 1/20 0.34
ADRB3 P13945 2/20 0.33
SRD5A1 P18405 1/20 0.31
ALDH1A3 P47895 2/20 0.30
ALDH3A1 P30838 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26108773 1.00 ALDH1A1 (0.38) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL26108437 0.81 ALDH1A1 (0.41) ALDH1A1GAAMAPTHPGDADRB2
SCHEMBL30629044 0.78 MAPT (0.38) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL26109423 0.78 MAPT (0.38) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL30629033 0.73 MEN1 (0.37) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL26110394 0.73 MAPT (0.37) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL30629068 0.73 MAPT (0.37) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL30629075 0.73 MAPT (0.37) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL26108155 0.73 MEN1 (0.37) ALDH1A1MEN1GAAMAPTHPGD
SCHEMBL30629095 0.73 MEN1 (0.37) ALDH1A1MEN1GAAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836157-A Oxadiazole derivative and preparation method and application thereof 星希尔生物科技(上海)有限公司 2023-10-03 CN disclosed