Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479942 | 1.00 | PRSS1 (0.40) | PRSS1PRSS2PRSS3CA2GPR84 | |
| SCHEMBL30787787 | 0.91 | GPR84 (0.40) | PRSS1PRSS2PRSS3CA2GPR84 | |
| SCHEMBL30693383 | 0.86 | ACE2 (0.45) | CA2GPR84CA1FFAR1LMNA | |
| SCHEMBL30306683 | 0.84 | ACE2 (0.42) | PRSS1CA2GPR84CA1FFAR1 | |
| SCHEMBL10081844 | 0.79 | TSHR (0.45) | CA2CA1TSHRTDP1CYP3A4 | |
| SCHEMBL22085912 | 0.78 | TSHR (0.55) | CA2CA1LMNATSHRTDP1 | |
| SCHEMBL27832482 | 0.76 | LMNA (0.33) | CA2CA1LMNATDP1ALDH1A1 | |
| SCHEMBL27832483 | 0.76 | LMNA (0.33) | CA2CA1LMNATDP1ALDH1A1 | |
| SCHEMBL27812358 | 0.76 | LMNA (0.33) | CA2CA1LMNAALDH1A1 | |
| SCHEMBL27812359 | 0.76 | LMNA (0.33) | CA2CA1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |