Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CD74 | P04233 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252252 | 1.00 | CA12 (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL13156347 | 0.87 | PKM (0.49) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL8218368 | 0.85 | MIF (0.53) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL29490178 | 0.83 | DDB1 (0.46) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL1161591 | 0.83 | DDB1 (0.46) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL8139447 | 0.82 | DDB1 (0.42) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL8190046 | 0.81 | DDB1 (0.41) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL13164129 | 0.81 | MIF (0.50) | CA12CA1CA2CA3CA4 | |
| SCHEMBL16413549 | 0.80 | ALDH1A1 (0.54) | DDB1CRBNIDO1KMT2AMIF | |
| SCHEMBL8184720 | 0.80 | IDH1 (0.43) | DDB1CRBNIDO1KMT2AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |