⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628097 | 1.00 | — | — | |
| SCHEMBL3063088 | 1.00 | — | — | |
| SCHEMBL23829876 | 1.00 | — | — | |
| SCHEMBL2205577 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3103866 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3088998 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3088996 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3103859 | 0.97 | — | — | |
| Trifluoroacetic Acid SCHEMBL3312307 | 0.87 | GABRP (0.75) | — | |
| Trifluoroacetic Acid SCHEMBL21724533 | 0.87 | GABRP (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995748-B1 | Growth hormone secretagogues | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | claimed |
| US-6686359-B2 | ANIMAL GROWTH REGULATORS; OSTEOPOROSIS; CONGESTIVE HEART FAILURE; MUSCULAR DISORDERS | PFIZER INC. | 2004-02-03 | — | — | US | claimed |
| US-20030130284-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2003-07-10 | — | — | US | claimed |
| US-6559150-B2 | Neurotransmitter stimulants; antidiabetic agents; congestive heart failure; obesity; frailty; maintaining renal and catabolic homeostasis; bone fracture repair; reducing cachexia and protein loss; muscle strength and burns. | PFIZER INC. | 2003-05-06 | — | — | US | claimed |
| US-20020045622-A1 | Growth hormone secretagogues | CARPINO PHILIP A (US) | 2002-04-18 | — | — | US | claimed |
| US-6358951-B1 | ADMINISTERING PYRAZOLO(4,3-C)PYRIDINE DERIVATIVE TO TREAT OBESITY, CONGESTIVE HEART FAILURE, OSTEOPOROSIS, AGING, BONE AND MUSCULAR DISORDERS | PFIZER INC. | 2002-03-19 | — | — | US | claimed |
| EP-0995748-A1 | Growth hormone secretagogues | Pfizer Products Inc. (US) | 2000-04-26 | — | — | EP | claimed |
| US-11998610-B2 | Conjugates and methods of using the same | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| CN-106661084-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2021-08-31 | — | — | CN | disclosed |
| EP-3836971-A1 | CONJUGATES AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2021-06-23 | — | — | EP | disclosed |
| US-20210162057-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-06-03 | — | — | US | disclosed |
| WO-2020037009-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-02-20 | — | — | WO | disclosed |
| US-10273208-B2 | Screening methods for the binding affinity of chemical entities to biological molecules and NEDD4-1 inhibitors identified by the screening methods | NORTHWESTERN UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| US-5025023-A | Fungicides, antitumor agents | BRISTOL-MYERS COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| US-4916063-A | FERMENTATION OF POLYANGIUM | BRISTOL-MYERS COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4898940-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-02-06 | — | — | US | disclosed |
| US-4833076-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| US-4777160-A | FUNGICIDES, ANTITUMOR, MICROBIOCIDES | BRISTOL-MYERS (US) | 1988-10-11 | — | — | US | disclosed |
| US-4692510-A | ANTIBIOTICS, ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| CN-86105469-A | Peptide antibiotic | — | 1987-06-10 | — | — | CN | disclosed |