Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.75 |
| ▸ | GABRD | O14764 | 2/20 | 0.75 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.75 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.75 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.75 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.75 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.75 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.75 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.75 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.75 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.75 |
| ▸ | GABRE | P78334 | 2/20 | 0.75 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.75 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.75 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.75 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.75 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3312297 | 1.00 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL21724195 | 1.00 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL21724533 | 1.00 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2205577 | 0.87 | — | — | |
| SCHEMBL6628097 | 0.87 | — | — | |
| SCHEMBL23829876 | 0.87 | — | — | |
| SCHEMBL3063088 | 0.87 | — | — | |
| SCHEMBL3063089 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL3103866 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL3088996 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113391-A1 | BICYCLIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2138482-A1 | BICYCLIC HETEROCYCLIC COMPOUND | Astellas Pharma Inc. (JP) | 2009-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113391-A1 | BICYCLIC HETEROCYCLIC COMPOUND | P2RY12, P2RY4, P2RY1 | GABRP 104/4885GABRD 79/4885GABRA1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.