Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404168 | 1.00 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 | |
| SCHEMBL14689214 | 0.95 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 | |
| SCHEMBL4908625 | 0.67 | KMT2A (0.43) | ALDH1A1L3MBTL1KDM4EMAPTCYP1A2 | |
| SCHEMBL857098 | 0.67 | KMT2A (0.46) | ALDH1A1L3MBTL1KDM4ENSD2CYP1A2 | |
| SCHEMBL11307009 | 0.67 | ABCB1 (0.47) | ALDH1A1L3MBTL1KDM4ECYP1A2KMT2A | |
| SCHEMBL18338949 | 0.66 | NPC1 (0.46) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 | |
| SCHEMBL14572400 | 0.64 | ACHE (0.50) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 | |
| SCHEMBL10828283 | 0.64 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 | |
| SCHEMBL1101904 | 0.64 | KDM4E (0.55) | ALDH1A1L3MBTL1KDM4EMAPTCYP3A4 | |
| SCHEMBL22881603 | 0.64 | KDM4E (0.46) | ALDH1A1L3MBTL1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741948-B | Saturated ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof | 日本烟草产业株式会社 | 2023-11-10 | — | — | CN | disclosed |