SCHEMBL30632045

SCHEMBL30632045

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nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAGI3 Q5TCQ9 1/20 0.39
▸ CPA1 P15085 1/20 0.38
▸ CPA2 P48052 1/20 0.38
▸ CPA4 Q9UI42 1/20 0.38
▸ MME P08473 1/20 0.36
▸ KEAP1 Q14145 2/20 0.36
▸ BACE1 P56817 2/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ F2 P00734 4/20 0.35
▸ IL23R Q5VWK5 1/20 0.35
▸ BACE2 Q9Y5Z0 1/20 0.34
▸ SYK P43405 2/20 0.34
▸ GNPAT O15228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30632044 0.92 PTPN1 (0.39) MAGI3MMEKEAP1PTPN1F2
SCHEMBL30632039 0.91 IL23R (0.40) MAGI3CPA1CPA2CPA4MME
SCHEMBL19051569 0.88 GNPAT (0.40) CPA1CPA2CPA4MMEBACE1
SCHEMBL30632042 0.88 BACE1 (0.40) MAGI3BACE1PTPN1IL23RBACE2
SCHEMBL21766761 0.87 BACE1 (0.41) MAGI3BACE1PTPN1BACE2
SCHEMBL21766737 0.86 MAGI3 (0.39) MAGI3KEAP1BACE1PTPN1BACE2
SCHEMBL30632040 0.85 FURIN (0.40) BACE1
SCHEMBL31094977 0.83 PTPN1 (0.46) KEAP1BACE1PTPN1F2BACE2
SCHEMBL31746072 0.83 PTPN1 (0.49) BACE1PTPN1BACE2
SCHEMBL29530913 0.83 MME (0.40) MAGI3MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11771774-B2 Nerve labeling compositions and uses thereof AVELAS ACQUISITION CORPORATION (US) 2023-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771774-B2 Nerve labeling compositions and uses thereof GAP43, NGF, PMP22 MAGI3 2150/4885CPA1 3343/4885CPA2 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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