Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | CPA2 | P48052 | 1/20 | 0.39 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051620 | 0.93 | GNPAT (0.44) | GNPATCPA1CPA2CPA4FOLH1 | |
| SCHEMBL11134385 | 0.91 | GNPAT (0.47) | GNPATPTPN1TNFMME | |
| SCHEMBL19051600 | 0.90 | NAALAD2 (0.37) | NAALAD2BACE1FOLH1RIMKLABMP1 | |
| SCHEMBL30561495 | 0.89 | ERAP2 (0.40) | NAALAD2BACE1FOLH1ERAP2BACE2 | |
| SCHEMBL30632045 | 0.88 | MAGI3 (0.39) | GNPATCPA1CPA2CPA4BACE1 | |
| SCHEMBL19051570 | 0.88 | NAALAD2 (0.39) | NAALAD2FOLH1RIMKLABMP1ERAP2 | |
| SCHEMBL20230298 | 0.88 | CPA1 (0.35) | GNPATCPA1CPA2CPA4BMP1 | |
| SCHEMBL31094977 | 0.88 | PTPN1 (0.46) | GNPATBACE1FOLH1ERAP2PTPN1 | |
| SCHEMBL6026424 | 0.88 | ALOX15 (0.42) | GNPATTNF | |
| SCHEMBL61370 | 0.88 | ALOX15 (0.42) | GNPATTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2017-06-29 | — | — | US | disclosed |
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2017-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | ACE, ACE2, MCTS1 | GNPAT 2714/4885CPA1 721/4885CPA2 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.