Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUND | P17535 | 1/20 | 0.34 |
| ▸ | FOSB | P53539 | 1/20 | 0.34 |
| ▸ | NRAS | P01111 | 6/20 | 0.33 |
| ▸ | FLT3 | P36888 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852920 | 0.84 | ACVR2A (0.37) | JUNDFOSBNRASFLT3KDM4E | |
| SCHEMBL29370090 | 0.81 | SUV39H2 (0.38) | KDM4EALDH1A1HPGDTSHRHTT | |
| SCHEMBL29682741 | 0.79 | PIK3CG (0.34) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL24542495 | 0.78 | FLT3 (0.42) | NRASFLT3PDE4DPDGFRBCDK7 | |
| SCHEMBL29682761 | 0.78 | FLT3 (0.42) | NRASFLT3PDE4DPDGFRBCDK7 | |
| SCHEMBL30698334 | 0.76 | KDM4E (0.32) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30632342 | 0.75 | KCNJ6 (0.31) | F2RL3 | |
| SCHEMBL29683000 | 0.75 | RBP4 (0.41) | ALDH1A1PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31639341 | 0.75 | PDE10A (0.34) | KDM4EALDH1A1HPGDMEN1TSHR | |
| SCHEMBL31000313 | 0.74 | SUV39H2 (0.33) | SUV39H2F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116887834-A | Polycyclic IRAK and flt3 inhibiting compounds and uses thereof | 儿童医院医学中心 | 2023-10-13 | — | — | CN | disclosed |