Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639175 | 0.77 | NRAS (0.36) | — | |
| SCHEMBL31000313 | 0.77 | SUV39H2 (0.33) | — | |
| SCHEMBL31639341 | 0.76 | PDE10A (0.34) | KDM4EALDH1A1MAPT | |
| SCHEMBL30632316 | 0.76 | JUND (0.34) | KDM4ENPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL31639455 | 0.75 | — | — | |
| SCHEMBL30852973 | 0.71 | ACVR2A (0.38) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL31639411 | 0.71 | NRAS (0.31) | — | |
| SCHEMBL31000272 | 0.71 | PDE4B (0.34) | MAPT | |
| SCHEMBL31639231 | 0.70 | HPGD (0.34) | KDM4EALDH1A1MAPT | |
| SCHEMBL31000296 | 0.69 | PDE4B (0.36) | NPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |
| EP-4540248-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023245123-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-21 | — | — | WO | disclosed |