Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 6/20 | 0.33 |
| ▸ | JAK3 | P52333 | 5/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684887 | 1.00 | KRAS (0.39) | KRASSMARCA2SMARCA4PBRM1EHMT2 | |
| SCHEMBL30632479 | 0.87 | OXTR (0.38) | KRASSMARCA2SMARCA4PBRM1EHMT2 | |
| SCHEMBL26684929 | 0.87 | OXTR (0.38) | KRASSMARCA2SMARCA4PBRM1EHMT2 | |
| SCHEMBL30632513 | 0.86 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1SYKALK | |
| SCHEMBL26685094 | 0.86 | SMARCA2 (0.39) | SMARCA2SMARCA4PBRM1SYKALK | |
| SCHEMBL26685179 | 0.86 | GPR119 (0.36) | KRASSMARCA2SMARCA4PBRM1EHMT2 | |
| SCHEMBL30632453 | 0.86 | GPR119 (0.36) | KRASSMARCA2SMARCA4PBRM1EHMT2 | |
| SCHEMBL30632436 | 0.85 | SMARCA2 (0.39) | KRASSMARCA2SMARCA4PBRM1ALK | |
| SCHEMBL26684679 | 0.85 | SMARCA2 (0.39) | KRASSMARCA2SMARCA4PBRM1ALK | |
| SCHEMBL31570165 | 0.82 | EGFR (0.32) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522278-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |