⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643006 | 0.77 | — | — | |
| SCHEMBL3569833 | 0.72 | — | — | |
| SCHEMBL7354141 | 0.70 | USP2 (0.46) | — | |
| SCHEMBL7348117 | 0.70 | — | — | |
| SCHEMBL6578001 | 0.69 | — | — | |
| SCHEMBL900920 | 0.69 | — | — | |
| SCHEMBL1118711 | 0.69 | USP2 (0.43) | — | |
| SCHEMBL23114724 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL2346906 | 0.67 | KDM4E (0.37) | — | |
| SCHEMBL2099384 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522614-A1 | 8- AND 6-SUBSTITUTED PYRIDOPYRIMIDINE DERIVATIVES AS KRAS INHIBITORS | Beta Pharma, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023219941-A1 | 8- AND 6-SUBSTITUTED PYRIDOPYRIMIDINE DERIVATIVES AS KRAS INHIBITORS | BETA PHARMA, INC. (US) | 2023-11-16 | — | — | WO | disclosed |