Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450544 | 1.00 | MTNR1A (0.51) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL20980913 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL13345363 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL10173839 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL430325 | 0.77 | SLC6A2 (0.49) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL27903505 | 0.77 | AADAT (0.42) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL4798469 | 0.77 | SLC6A2 (0.49) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL23917061 | 0.77 | NOTUM (0.39) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL6341407 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BNOTUMHTR2AHTR2C | |
| SCHEMBL11667313 | 0.77 | MTNR1A (0.56) | MTNR1AMTNR1BNOTUMESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192375-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. (US) | 2023-10-05 | — | — | WO | disclosed |