Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049170 | 0.79 | MAPT (0.69) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9978289 | 0.79 | MAPT (0.69) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14935499 | 0.79 | MAPT (0.69) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11296000 | 0.77 | MAPT (0.67) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11299049 | 0.77 | MAPT (0.67) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30632929 | 0.76 | MAPT (0.53) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL660647 | 0.75 | NPC1 (0.60) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL660646 | 0.75 | NPC1 (0.60) | SOS1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL30633018 | 0.74 | MAPT (0.60) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL18640449 | 0.74 | MAPT (0.60) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |