Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632939 | 0.80 | NPC1 (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30632963 | 0.79 | NFE2L2 (0.55) | KDM4EL3MBTL1NPC1RAB9APKM | |
| SCHEMBL30632896 | 0.78 | HTR2A (0.40) | MAPTALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL15870902 | 0.77 | — | — | |
| SCHEMBL30632980 | 0.76 | SOS1 (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30632909 | 0.76 | NFKB1 (0.45) | RAB9ANFE2L2NFKB1 | |
| SCHEMBL30632983 | 0.75 | NAPRT (0.36) | MAPTKDM4ENPC1RAB9APKM | |
| SCHEMBL2278846 | 0.74 | GRM4 (0.44) | MAPTALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL2278845 | 0.74 | GRM4 (0.44) | MAPTALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL1058814 | 0.74 | ALDH1A1 (0.62) | MAPTALDH1A1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886234-B | Heterocyclic mitochondrial activity inhibitors and uses thereof | 蒙特利尔大学 | 2023-12-15 | — | — | CN | disclosed |