Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 3/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 7/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.42 |
| ▸ | CHUK | O15111 | 6/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.42 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686550 | 1.00 | CCNK (0.46) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL26686212 | 0.92 | CCNK (0.40) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL30633347 | 0.92 | CCNK (0.40) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL26685815 | 0.84 | NUDT1 (0.44) | CCNKCDK12CAMKK2CHUKMAPK8 | |
| SCHEMBL30633136 | 0.84 | NUDT1 (0.44) | CCNKCDK12CAMKK2CHUKMAPK8 | |
| SCHEMBL26686752 | 0.83 | CCNK (0.52) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL31240468 | 0.83 | CCNK (0.52) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL26686660 | 0.80 | KDM5B (0.33) | CCNKCDK12TBK1CHUK | |
| SCHEMBL26686396 | 0.79 | CCNK (0.41) | CCNKCDK12CAMKK2TBK1CHUK | |
| SCHEMBL26686177 | 0.79 | IKBKB (0.42) | TBK1CHUKJAK2PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |