Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 3/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.38 |
| ▸ | CHUK | O15111 | 10/20 | 0.34 |
| ▸ | IKBKB | O14920 | 9/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | CIT | O14578 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685815 | 1.00 | NUDT1 (0.44) | NUDT1CCNKCDK12CHUKIKBKB | |
| SCHEMBL26685805 | 0.86 | CHUK (0.37) | NUDT1CCNKCDK12CHUKIKBKB | |
| SCHEMBL30633151 | 0.86 | CHUK (0.37) | NUDT1CCNKCDK12CHUKIKBKB | |
| SCHEMBL26686177 | 0.85 | IKBKB (0.42) | CHUKIKBKBROCK1CLK2DYRK1A | |
| SCHEMBL26686660 | 0.85 | KDM5B (0.33) | NUDT1CCNKCDK12CHUKIKBKB | |
| SCHEMBL26686550 | 0.84 | CCNK (0.46) | CCNKCDK12CHUKJAK2INSR | |
| SCHEMBL30633292 | 0.84 | CCNK (0.46) | CCNKCDK12CHUKJAK2INSR | |
| SCHEMBL30633155 | 0.83 | NUDT1 (0.38) | NUDT1CCNKCDK12CHUKCLK2 | |
| SCHEMBL26686416 | 0.83 | NUDT1 (0.38) | NUDT1CCNKCDK12CHUKCLK2 | |
| SCHEMBL30633347 | 0.82 | CCNK (0.40) | CCNKCDK12CHUKAURKBINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | claimed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | claimed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | claimed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |