Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 6/20 | 0.48 |
| ▸ | KDR | P35968 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.43 |
| ▸ | PLK4 | O00444 | 3/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | MARK3 | P27448 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 3/20 | 0.41 |
| ▸ | CLK2 | P49760 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633303 | 0.93 | JAK2 (0.48) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL30633336 | 0.91 | KDR (0.51) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL30633377 | 0.90 | JAK2 (0.51) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL30633315 | 0.90 | JAK2 (0.46) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL30633323 | 0.88 | CNR1 (0.61) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL26686359 | 0.88 | CNR1 (0.61) | CNR1JAK2KDRMAPK1PLK4 | |
| SCHEMBL30633326 | 0.87 | DYRK1A (0.45) | JAK2MAPK1CLK2DYRK1A | |
| SCHEMBL30633386 | 0.86 | JAK2 (0.41) | JAK2KDRMAPK1PLK4DAPK3 | |
| SCHEMBL30633320 | 0.86 | KDR (0.46) | JAK2KDRMAPK1PLK4DAPK3 | |
| SCHEMBL30633368 | 0.81 | JAK2 (0.38) | JAK2KDRMAPK1PLK4DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |