Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.46 |
| ▸ | KIT | P10721 | 10/20 | 0.46 |
| ▸ | FLT3 | P36888 | 7/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.39 |
| ▸ | CSF1R | P07333 | 5/20 | 0.39 |
| ▸ | FLT1 | P17948 | 5/20 | 0.39 |
| ▸ | FLT4 | P35916 | 5/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.39 |
| ▸ | MARK2 | Q7KZI7 | 5/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.39 |
| ▸ | MARK3 | P27448 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633303 | 0.91 | JAK2 (0.48) | KDRKITFLT3JAK2F11 | |
| SCHEMBL30633336 | 0.90 | KDR (0.51) | KDRKITFLT3PDGFRAJAK2 | |
| SCHEMBL30633299 | 0.89 | KDR (0.51) | KDRKITFLT3PDGFRAJAK2 | |
| SCHEMBL26686267 | 0.89 | KDR (0.51) | KDRKITFLT3PDGFRAJAK2 | |
| SCHEMBL30633386 | 0.89 | JAK2 (0.41) | KDRKITFLT3JAK2MAPK1 | |
| SCHEMBL30633326 | 0.88 | DYRK1A (0.45) | JAK2MAPK1DYRK1ACLK2 | |
| SCHEMBL30633306 | 0.86 | CNR1 (0.51) | KDRKITFLT3JAK2MAPK1 | |
| SCHEMBL30633377 | 0.84 | JAK2 (0.51) | KDRKITFLT3JAK2MAPK1 | |
| SCHEMBL30633315 | 0.84 | JAK2 (0.46) | KDRKITFLT3JAK2MAPK1 | |
| SCHEMBL30633368 | 0.80 | JAK2 (0.38) | KDRJAK2F11MAPK1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |