Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.51 |
| ▸ | KIT | P10721 | 5/20 | 0.47 |
| ▸ | FLT3 | P36888 | 4/20 | 0.47 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | BLK | P51451 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633303 | 0.92 | JAK2 (0.48) | KDRKITFLT3JAK2JAK1 | |
| SCHEMBL30633306 | 0.91 | CNR1 (0.51) | KDRKITFLT3JAK2JAK1 | |
| SCHEMBL30633386 | 0.90 | JAK2 (0.41) | KDRKITFLT3JAK2JAK1 | |
| SCHEMBL30633320 | 0.90 | KDR (0.46) | KDRKITFLT3JAK2LCK | |
| SCHEMBL26685808 | 0.88 | KDR (0.62) | KDRKITFLT3VHLJAK2 | |
| SCHEMBL30633365 | 0.88 | KDR (0.62) | KDRKITFLT3VHLJAK2 | |
| SCHEMBL30633326 | 0.88 | DYRK1A (0.45) | JAK2CLK2MAPK1 | |
| SCHEMBL30633377 | 0.85 | JAK2 (0.51) | KDRKITFLT3JAK2JAK1 | |
| SCHEMBL30633315 | 0.84 | JAK2 (0.46) | KDRKITFLT3JAK2CNR1 | |
| SCHEMBL30633352 | 0.80 | JAK2 (0.56) | KDRKITFLT3JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |