Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 12/20 | 0.53 |
| ▸ | JAK1 | P23458 | 8/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | MARK3 | P27448 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685861 | 0.90 | JAK2 (0.56) | JAK2JAK1KDRMAPK1CNR1 | |
| SCHEMBL30633352 | 0.90 | JAK2 (0.56) | JAK2JAK1KDRMAPK1CNR1 | |
| SCHEMBL30633312 | 0.89 | JAK2 (0.45) | JAK2JAK1MAPK1CNR1DYRK1A | |
| SCHEMBL31420124 | 0.86 | JAK2 (0.61) | JAK2JAK1KDRMAPK1CNR1 | |
| SCHEMBL26686370 | 0.86 | JAK2 (0.61) | JAK2JAK1KDRMAPK1CNR1 | |
| SCHEMBL30633321 | 0.84 | KDR (0.52) | JAK2JAK1KDRMAPK1KIT | |
| SCHEMBL26686360 | 0.84 | KDR (0.52) | JAK2JAK1KDRMAPK1KIT | |
| SCHEMBL26686302 | 0.83 | JAK2 (0.46) | JAK2JAK1KDRMAPK1CDK1 | |
| SCHEMBL30633358 | 0.83 | JAK2 (0.46) | JAK2JAK1KDRMAPK1CDK1 | |
| SCHEMBL30633313 | 0.82 | JAK2 (0.45) | JAK2JAK1MAPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |