Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.44 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | CLK3 | P49761 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26685885 | 0.94 | MMP13 (0.49) | MMP13NUDT1JAK2TYK2JAK3 | |
| SCHEMBL31240624 | 0.94 | MMP13 (0.49) | MMP13NUDT1JAK2TYK2JAK3 | |
| SCHEMBL31240758 | 0.89 | MMP13 (0.44) | MMP13NUDT1JAK2TYK2JAK3 | |
| SCHEMBL30633398 | 0.85 | NUDT1 (0.46) | NUDT1JAK2TYK2JAK3JAK1 | |
| SCHEMBL26686152 | 0.85 | NUDT1 (0.46) | NUDT1JAK2TYK2JAK3JAK1 | |
| SCHEMBL30633340 | 0.83 | NUDT1 (0.49) | MMP13NUDT1DYRK1AHPGD | |
| SCHEMBL17126117 | 0.81 | NUDT1 (0.48) | MMP13NUDT1BRAFMMP2MMP14 | |
| SCHEMBL31240425 | 0.80 | NUDT1 (0.48) | NUDT1JAK2TYK2JAK3JAK1 | |
| SCHEMBL31420159 | 0.80 | NUDT1 (0.60) | NUDT1JAK2TYK2JAK3JAK1 | |
| SCHEMBL26686408 | 0.80 | NUDT1 (0.48) | NUDT1JAK2TYK2JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |