Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.53 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | PRKCH | P24723 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.53 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548186 | 1.00 | NPSR1 (0.63) | NPSR1TLR7HTR2CPRKD3PRKCG | |
| SCHEMBL2553228 | 0.84 | HTR2B (0.70) | NPSR1TLR7TDP1ALDH1A1MAPT | |
| SCHEMBL2551781 | 0.83 | NPSR1 (0.71) | NPSR1TLR7PRKD3PRKCGPRKCB | |
| SCHEMBL2554136 | 0.82 | HDAC6 (0.52) | NPSR1TLR7TDP1ALDH1A1MAPT | |
| SCHEMBL30634999 | 0.82 | ACHE (0.51) | NPSR1TLR7TDP1ALDH1A1MAPT | |
| SCHEMBL2691637 | 0.81 | ACHE (0.61) | TLR7HTR2CPRKD3PRKCGPRKCB | |
| SCHEMBL6984602 | 0.81 | HTR2C (0.55) | NPSR1TLR7HTR2CTDP1ALDH1A1 | |
| SCHEMBL11511135 | 0.80 | HDAC1 (0.74) | NPSR1TLR7TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL2552404 | 0.79 | SHMT2 (0.52) | NPSR1TLR7ALDH1A1MAPTKDM4E | |
| Hydrazine SCHEMBL27906351 | 0.79 | HDAC1 (0.72) | NPSR1TLR7TDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969929-A | 2- (sulfinyl-5- (2-phenylthiazol-4-yl) -1,3, 4-oxa (thia) diazole compounds, and preparation method and application thereof | 长江大学 | 2023-10-31 | — | — | CN | disclosed |