Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635452 | 0.88 | HRH3 (0.52) | HRH3KDM4EBCL2L1MEN1KMT2A | |
| SCHEMBL30635458 | 0.82 | HRH3 (0.54) | HRH3POLB | |
| SCHEMBL30635451 | 0.80 | SIGMAR1 (0.36) | HRH3BCL2L1MEN1KMT2ACASP1 | |
| SCHEMBL30635521 | 0.78 | HRH3 (0.42) | HRH3MC4RCHKASYKLMNA | |
| SCHEMBL14566661 | 0.78 | MC4R (0.53) | HRH3MC4RCHKALMNACA2 | |
| SCHEMBL25177979 | 0.77 | TAAR1 (0.55) | HRH3KDM4EMEN1KMT2ACASP1 | |
| SCHEMBL31010217 | 0.77 | HRH3 (0.57) | HRH3POLBKDM4E | |
| SCHEMBL21565496 | 0.77 | CHKA (0.59) | HRH3MC4RCHKANCF1 | |
| SCHEMBL30635453 | 0.77 | ALDH1A1 (0.41) | HRH3 | |
| SCHEMBL19490801 | 0.76 | MC4R (0.56) | HRH3MC4RCHKALMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |