Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855853 | 0.90 | CYP1A1 (0.49) | CYP1A2CYP1A1CYP1B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5128314 | 0.89 | CYP1A1 (0.56) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL31305440 | 0.89 | CYP1A1 (0.56) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL27824986 | 0.84 | CYP1A1 (0.50) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL7141855 | 0.83 | KDM4E (0.45) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL26110507 | 0.83 | KDM4E (0.45) | MEN1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL31305475 | 0.83 | CYP1A1 (0.53) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL2950013 | 0.83 | CYP1A1 (0.53) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL17280243 | 0.83 | CYP1A1 (0.49) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL30635831 | 0.83 | NPC1 (0.45) | CYP1A2CYP2A6MEN1KMT2ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500562-B1 | SUBSTITUTED AZOLE DERIVATIVES FOR GENERATION, PROLIFERATION AND DIFFERENTIATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | NAT UNIV SINGAPORE (SG) | 2023-11-15 | — | — | EP | claimed |
| EP-3500562-B1 | SUBSTITUTED AZOLE DERIVATIVES FOR GENERATION, PROLIFERATION AND DIFFERENTIATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | NAT UNIV SINGAPORE (SG) | 2023-11-15 | — | — | EP | disclosed |