Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7140665 | 0.85 | MAPK13 (0.48) | NPC1RAB9AMEN1USP2ALOX15 | |
| SCHEMBL30635827 | 0.83 | CYP1A2 (0.48) | NPC1RAB9AMEN1KMT2ACYP1A1 | |
| SCHEMBL7144910 | 0.79 | PDGFRB (0.54) | NPC1RAB9AMEN1USP2ALOX15 | |
| SCHEMBL11771726 | 0.78 | KDM4E (0.50) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL17279819 | 0.77 | NPC1 (0.50) | NPC1RAB9ACASP3SENP7MAPT | |
| SCHEMBL15029205 | 0.76 | MAPK1 (0.42) | NPC1RAB9AMEN1KMT2AMAPK14 | |
| SCHEMBL28289637 | 0.74 | PDGFRB (0.54) | CYP1A2MAPTCYP2C9PDGFRB | |
| SCHEMBL7140253 | 0.74 | NPC1 (0.51) | NPC1RAB9AMEN1USP2ALOX15 | |
| SCHEMBL4855853 | 0.74 | CYP1A1 (0.49) | NPC1RAB9ACYP1A1CYP1B1CYP11B2 | |
| SCHEMBL17280243 | 0.74 | CYP1A1 (0.49) | NPC1RAB9AMEN1KMT2ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500562-B1 | SUBSTITUTED AZOLE DERIVATIVES FOR GENERATION, PROLIFERATION AND DIFFERENTIATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | NAT UNIV SINGAPORE (SG) | 2023-11-15 | — | — | EP | claimed |
| EP-3500562-B1 | SUBSTITUTED AZOLE DERIVATIVES FOR GENERATION, PROLIFERATION AND DIFFERENTIATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | NAT UNIV SINGAPORE (SG) | 2023-11-15 | — | — | EP | disclosed |