Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305440 | 0.95 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5128314 | 0.95 | CYP1A1 (0.56) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30635827 | 0.90 | CYP1A2 (0.48) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL27824986 | 0.90 | CYP1A1 (0.50) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL31305475 | 0.89 | CYP1A1 (0.53) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2950013 | 0.89 | CYP1A1 (0.53) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17280243 | 0.89 | CYP1A1 (0.49) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26111983 | 0.85 | CTRC (0.51) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29662878 | 0.84 | MAPK14 (0.53) | CYP1A1CYP1B1CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17280181 | 0.84 | MEN1 (0.43) | CYP1A1CYP1B1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | NISHIO TETSUYA | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | PIEZO1, YES1, SAT1 | CYP1A1 2605/4885CYP1B1 2037/4885CYP1A2 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.