Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956334 | 0.77 | IMPDH2 (0.56) | MAPK14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1387159 | 0.76 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL91416 | 0.74 | RAB9A (0.59) | MAPK14NPC1RAB9ACSNK1DCSNK1E | |
| SCHEMBL25785269 | 0.73 | NPC1 (0.57) | MAPK14NPC1RAB9ACSNK1DCSNK1E | |
| SCHEMBL6747565 | 0.71 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL4470256 | 0.71 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11NR3C2 | |
| SCHEMBL1387433 | 0.71 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11NR3C2 | |
| SCHEMBL3064617 | 0.71 | MAPK14 (0.57) | MAPK14NPC1RAB9ACSNK1DCSNK1E | |
| SCHEMBL3270030 | 0.71 | MAPK14 (0.71) | MAPK14MEN1KMT2AMAPK13MAPK12 | |
| SCHEMBL6708437 | 0.71 | MAPK14 (0.71) | MAPK14RAB9AMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500562-B1 | SUBSTITUTED AZOLE DERIVATIVES FOR GENERATION, PROLIFERATION AND DIFFERENTIATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS | NAT UNIV SINGAPORE (SG) | 2023-11-15 | — | — | EP | claimed |