Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.78 |
| ▸ | ITGAV | P06756 | 15/20 | 0.78 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.76 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.76 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.70 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.70 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclorgdfv SCHEMBL29384091 | 1.00 | ITGB3 (0.78) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL31294830 | 0.92 | ITGB3 (0.80) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| SCHEMBL30098352 | 0.91 | ITGB3 (0.76) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| SCHEMBL29464836 | 0.89 | ITGB3 (0.75) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| SCHEMBL29578997 | 0.89 | ITGB3 (0.75) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| SCHEMBL29366713 | 0.88 | ITGB3 (0.74) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| SCHEMBL30129817 | 0.88 | ITGB3 (0.81) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| SCHEMBL17364341 | 0.88 | ITGB3 (0.74) | ITGB3ITGAVITGB5ITGA2BITGA5 | |
| Cilengitide SCHEMBL19534260 | 0.87 | ITGB3 (0.78) | ITGB3ITGAVITGB5ITGA2BITGB6 | |
| Cilengitide SCHEMBL34082 | 0.87 | ITGB3 (0.78) | ITGB3ITGAVITGB5ITGA2BITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981479-A | FAP-activated radiation therapy diagnostic method and use relating thereto | 塔夫茨大学信托人 | 2023-10-31 | — | — | CN | claimed |
| CN-116981479-A | FAP-activated radiation therapy diagnostic method and use relating thereto | 塔夫茨大学信托人 | 2023-10-31 | — | — | CN | disclosed |