Cyclorgdfv

Cyclorgdfv

SCHEMBL29384091

CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC1=O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.78
ITGAV P06756 15/20 0.78
ITGB5 P18084 8/20 0.76
ITGA2B P08514 7/20 0.76
ITGB6 P18564 3/20 0.76
ITGA5 P08648 3/20 0.70
ITGB1 P05556 2/20 0.70
ITGB8 P26012 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclorgdfv SCHEMBL30636069 1.00 ITGB3 (0.78) ITGB3ITGAVITGB5ITGA2BITGB6
SCHEMBL31294830 0.92 ITGB3 (0.80) ITGB3ITGAVITGB5ITGA2BITGA5
SCHEMBL30098352 0.91 ITGB3 (0.76) ITGB3ITGAVITGB5ITGA2BITGA5
SCHEMBL29464836 0.89 ITGB3 (0.75) ITGB3ITGAVITGB5ITGA2BITGA5
SCHEMBL29578997 0.89 ITGB3 (0.75) ITGB3ITGAVITGB5ITGA2BITGA5
SCHEMBL29366713 0.88 ITGB3 (0.74) ITGB3ITGAVITGB5ITGA2BITGA5
SCHEMBL30129817 0.88 ITGB3 (0.81) ITGB3ITGAVITGB5ITGA2BITGB6
SCHEMBL17364341 0.88 ITGB3 (0.74) ITGB3ITGAVITGB5ITGA2BITGA5
Cilengitide SCHEMBL19534260 0.87 ITGB3 (0.78) ITGB3ITGAVITGB5ITGA2BITGB6
Cilengitide SCHEMBL34082 0.87 ITGB3 (0.78) ITGB3ITGAVITGB5ITGA2BITGB6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY BeijingGiluntidePharmaceuticalCo.,Ltd. (CN) 2025-09-25 US claimed
US-12351855-B2 Bioelectronic circuits, systems and methods for preparing and using them ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-07-08 US claimed
CN-119896744-A Application of integrin targeting peptide-collagenase pharmaceutical composition and pharmaceutical composition constructed by same 中国药科大学 2025-04-29 CN claimed
CN-119838022-A Amatoxin conjugates containing branched linkers 杭州多禧生物科技有限公司 2025-04-18 CN claimed
US-12220464-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-02-11 US claimed
WO-2024239281-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
WO-2024240173-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
CN-115443134-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2022-12-06 CN claimed
US-20220378951-A1 SPECIFIC CONJUGATION LINKERS, SPECIFIC IMMUNOCONJUGATES THEREOF, METHODS OF MAKING AND USES SUCH CONJUGATES THEREOF HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-01 US claimed
US-20220313836-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-10-06 US claimed
WO-2022184899-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FACELLITATE GMBH (DE) 2022-09-09 WO claimed
EP-4053163-A1 CELL ATTACHMENT MATERIALS, DEVICES AND USES THEREOF FaCellitate GmbH (DE) 2022-09-07 EP claimed
WO-2022133288-A1 FAP-ACTIVATED RADIOTHERANOSTICS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE (US) 2022-06-23 WO claimed
EP-3986463-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2022-04-27 EP claimed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO claimed
US-20220098635-A1 BIOELECTRONIC CIRCUITS, SYSTEMS AND METHODS FOR PREPARING AND USING THEM ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-03-31 US claimed
CN-114040779-A Conjugates of cell binding molecules containing branched linkers and cytotoxic agents 杭州多禧生物科技有限公司 2022-02-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295821-A1 TARGETED RADIOPHARMACEUTICAL FOR TUMOR AND ITS USE IN THE IMAGING-GUIDED COMBINATION THERAPY OF TARGETED RADIOTHERAPY AND IMMUNOTHERAPY CD274, ITGB1, ITGA1 ITGB3 6/4885ITGAV 5/4885ITGB5 22/4885
US-20220313836-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS CD2BP2, DCLRE1A, EPCAM ITGB3 265/4885ITGAV 791/4885ITGB5 503/4885
US-12220464-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof SLC25A1, GCDH, FH ITGB3 2189/4885ITGAV 2755/4885ITGB5 1545/4885
US-20220378951-A1 SPECIFIC CONJUGATION LINKERS, SPECIFIC IMMUNOCONJUGATES THEREOF, METHODS OF MAKING AND USES SUCH CONJUGATES THEREOF SLC25A1, GCDH, FH ITGB3 2189/4885ITGAV 2755/4885ITGB5 1545/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 ITGB3 55/4885ITGAV 549/4885ITGB5 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.