SCHEMBL30636596

SCHEMBL30636596

CCOC(OCC)[C@@H](N)c1cccc(C)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.43
IDO1 P14902 2/20 0.37
ACHE P22303 2/20 0.37
FFAR1 O14842 1/20 0.36
ACP3 P15309 1/20 0.36
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KCNA5 P22460 1/20 0.34
KCNH2 Q12809 1/20 0.34
KCNB1 Q14721 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
TACR1 P25103 2/20 0.34
CYP19A1 P11511 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30636594 0.80 AOC3 (0.48) AOC3IDO1TAAR1
SCHEMBL3170486 0.80 DPP4 (0.52) TAAR1TACR1
SCHEMBL3259002 0.79 ACHE (0.52) AOC3IDO1ACHEACP3TAAR1
SCHEMBL12569050 0.79 ACHE (0.52) AOC3IDO1ACHEACP3TAAR1
SCHEMBL3254719 0.79 ACHE (0.52) AOC3IDO1ACHEACP3TAAR1
SCHEMBL7926083 0.78 AOC3 (0.44) AOC3IDO1ACHEFFAR1ACP3
SCHEMBL30636602 0.75 SLC6A2 (0.47) AOC3KCNH2SLC6A2SLC6A4
SCHEMBL23241790 0.74 AOC3 (0.46) AOC3ACHEACP3TAAR1
SCHEMBL30636593 0.72 MEN1 (0.36) FFAR1
SCHEMBL4172487 0.72 AOC3 (0.45) AOC3IDO1ACHEACP3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113816865-B Preparation method of chiral alpha-amino acetal compound and derivative thereof 南方科技大学 2023-12-19 CN disclosed