Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395991 | 0.89 | NOX1 (0.43) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL14579767 | 0.85 | MAP4K4 (0.47) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL28296998 | 0.84 | NOX1 (0.45) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL30320785 | 0.84 | NOX1 (0.44) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL29922981 | 0.81 | MAP4K4 (0.50) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL28647943 | 0.81 | MAP4K4 (0.50) | NPC1RAB9APOLBDYRK1ANOX1 | |
| SCHEMBL30171053 | 0.81 | MAP4K4 (0.52) | NPC1RAB9APOLBDYRK1ALMNA | |
| SCHEMBL5323937 | 0.81 | MAP4K4 (0.52) | NPC1RAB9APOLBDYRK1ALMNA | |
| SCHEMBL2062423 | 0.79 | TNKS (0.49) | NPC1DYRK1ANOX1KDM4EMAPT | |
| SCHEMBL18574377 | 0.79 | TNKS (0.48) | NPC1RAB9APOLBDYRK1ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854689-B | Imidazole [4,5f ] [1,10] phenanthroline compound, and preparation method and application thereof | 中国药科大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-116854689-A | Imidazole [4,5f ] [1,10] phenanthroline compound, and preparation method and application thereof | 中国药科大学 | 2023-10-10 | — | — | CN | disclosed |