Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620785 | 0.92 | KDM4E (0.54) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15828354 | 0.92 | KDM4E (0.54) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28026184 | 0.91 | KDM4E (0.53) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL3824137 | 0.79 | GRIN2D (0.43) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7261951 | 0.79 | KDM4E (0.53) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6227985 | 0.79 | KDM4E (0.53) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL818887 | 0.79 | GRIN2D (0.43) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL819043 | 0.78 | GRIN2D (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29494130 | 0.78 | GRIN2D (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31465572 | 0.78 | GRIN2D (0.45) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | disclosed |