Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | NPY4R | P50391 | 10/20 | 0.53 |
| ▸ | NPY1R | P25929 | 8/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.53 |
| ▸ | NPY2R | P49146 | 4/20 | 0.53 |
| ▸ | VIPR2 | P41587 | 4/20 | 0.51 |
| ▸ | VIPR1 | P32241 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239836 | 0.93 | BACE1 (0.58) | BACE1VIPR2VIPR1BACE2 | |
| SCHEMBL30507401 | 0.92 | BACE1 (0.59) | BACE1VIPR2VIPR1 | |
| SCHEMBL29860217 | 0.91 | BACE1 (0.56) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31657703 | 0.90 | KISS1R (0.53) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30637766 | 0.90 | BACE1 (0.55) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31468447 | 0.90 | NPY4R (0.53) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29859954 | 0.89 | NPY4R (0.59) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30866920 | 0.89 | NPY4R (0.58) | BACE1NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30543294 | 0.88 | BACE1 (0.53) | BACE1NPY4RNPY1RNPY5RVIPR2 | |
| SCHEMBL30350355 | 0.88 | BACE1 (0.61) | BACE1NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497644-B2 | Subtilisin variants and their use | Fresenius Kabi Ipsum S.R.L. (IT) | 2025-12-16 | — | — | US | claimed |
| US-20240043897-A1 | SUBTILISIN VARIANTS AND THEIR USE | Fresenius Kabi Ipsum S.R.L. (IT) | 2024-02-08 | — | — | US | claimed |
| CN-117098843-A | Subtilisin variants and uses thereof | 费森尤斯卡比有限公司 | 2023-11-21 | — | — | CN | claimed |
| US-12497644-B2 | Subtilisin variants and their use | Fresenius Kabi Ipsum S.R.L. (IT) | 2025-12-16 | — | — | US | disclosed |
| US-20250122260-A1 | GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) ANALOGUES | ZEALAND PHARMA A/S (DK) | 2025-04-17 | — | — | US | disclosed |
| CN-117098843-A | Subtilisin variants and uses thereof | 费森尤斯卡比有限公司 | 2023-11-21 | — | — | CN | disclosed |