SCHEMBL31468447

SCHEMBL31468447

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.53
NPY1R P25929 6/20 0.53
NPY2R P49146 4/20 0.53
NPY5R Q15761 4/20 0.53
BACE1 P56817 2/20 0.50
F2 P00734 2/20 0.47
KISS1R Q969F8 2/20 0.46
KEAP1 Q14145 1/20 0.46
CTSD P07339 1/20 0.46
BACE2 Q9Y5Z0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31657703 0.92 KISS1R (0.53) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30350355 0.91 BACE1 (0.61) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30637754 0.90 BACE1 (0.57) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29612206 0.88 BACE1 (0.54) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30291915 0.87 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL30798296 0.87 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL26254802 0.87 NPY4R (0.59) NPY4RNPY1RNPY2RNPY5RF2
SCHEMBL29493332 0.86 NPY4R (0.58) NPY4RNPY1RNPY2RNPY5RKEAP1
SCHEMBL7420426 0.86 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29631906 0.86 KEAP1 (0.52) NPY4RNPY1RNPY2RNPY5RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122260-A1 GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) ANALOGUES ZEALAND PHARMA A/S (DK) 2025-04-17 US disclosed