Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | DDO | Q99489 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647980 | 0.80 | DAO (0.51) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL15416243 | 0.74 | KDM4E (0.55) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL828487 | 0.74 | BRD4 (0.59) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL31394 | 0.70 | KDM4E (0.59) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL29364659 | 0.70 | KDM4E (0.59) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL11388942 | 0.70 | SRC (0.54) | MAPK1 | |
| Hydrochloric Acid SCHEMBL22159198 | 0.70 | BRD4 (0.54) | DAODDOKDM4EHPGDHSD17B10 | |
| SCHEMBL34468859 | 0.70 | SMYD3 (0.52) | DAODDO | |
| SCHEMBL30838562 | 0.70 | KDM4E (0.49) | DAODDOFLT3KDM4EHPGD | |
| SCHEMBL5475936 | 0.70 | KDM4E (0.48) | DAODDOKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549010-B | Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof | 中国科学院上海药物研究所 | 2023-10-20 | — | — | CN | disclosed |