Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | DAO | P14920 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | DDO | Q99489 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364659 | 1.00 | KDM4E (0.59) | KDM4EDAOMAPTHPGDSRD5A2 | |
| Hydrochloric Acid SCHEMBL5027809 | 0.98 | KDM4E (0.58) | KDM4EDAOMAPTHPGDSRD5A2 | |
| Fluoride SCHEMBL29664116 | 0.98 | KDM4E (0.58) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL27578750 | 0.89 | KDM4E (0.49) | KDM4EDAOMAPTHPGDSRD5A2 | |
| Glycerin SCHEMBL27539640 | 0.88 | KDM4E (0.48) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL1367711 | 0.87 | DAO (0.61) | KDM4EDAOMAPTHPGDSRD5A2 | |
| Quinoline SCHEMBL11495860 | 0.85 | PADI4 (0.50) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL16627746 | 0.84 | DAO (0.58) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL29390425 | 0.84 | DAO (0.58) | KDM4EDAOMAPTHPGDSRD5A2 | |
| SCHEMBL29505966 | 0.84 | DAO (0.58) | KDM4EDAOMAPTHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | claimed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | claimed |
| CN-113185505-A | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2021-07-30 | — | — | CN | claimed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-3784656-A1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | Bayer Animal Health GmbH (DE) | 2021-03-03 | — | — | EP | claimed |
| CN-106674254-B | Quinolone carboxylic acid compounds and intermediates, preparation method and application thereof | 广东省中医院 | 2019-03-15 | — | — | CN | claimed |
| CN-109251211-A | A kind of quinolonecarboxylic acid compound and its intermediate, preparation method and application | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2019-01-22 | — | — | CN | claimed |
| US-9994444-B2 | Bridged polycyclic compound based compositions for the inhibition and amelioration of disease | ALLACCEM, INC. (US) | 2018-06-12 | — | — | US | claimed |
| CN-106674254-A | Quinolone carboxylic acid compounds and intermediates, preparation method and application thereof | 广东省中医院 | 2017-05-17 | — | — | CN | claimed |
| CN-106572982-A | Antimicrobial compositions with effervescent agents | 梅琳塔治疗公司 | 2017-04-19 | — | — | CN | claimed |
| EP-0176846-B1 | 3-AMINO-2-BENZOYL-ACRYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-08-16 | — | — | EP | claimed |
| EP-0311948-A2 | Quinolonecarboxylic acid compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-19 | — | — | EP | claimed |
| US-4680401-A | Preparation of halogenated quinolonecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-14 | — | — | US | claimed |
| CN-86104256-A | 1, the preparation method of 8-bridging 4-quinolone-3-carboxylic-acid | — | 1987-03-18 | — | — | CN | claimed |
| EP-0117473-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0117474-B1 | QUINOLONE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1986-10-29 | — | — | EP | claimed |
| EP-0118854-B1 | BACTERICIDAL AGENT CONTAINING QUINOLONE-CARBOXYLIC ACIDS | BAYER AG (DE) | 1986-07-23 | — | — | EP | claimed |
| US-4559341-A | Quinolonecarboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | claimed |
| US-4559342-A | Quinolone acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | claimed |
| EP-0012925-B1 | QUINOLON-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | NQO2, PGD, ALAD | KDM4E 2839/4885DAO 176/4885MAPT 4256/4885 |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | NQO2, PGD, ALAD | KDM4E 2839/4885DAO 176/4885MAPT 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.