Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.70 |
| ▸ | CTSS | P25774 | 1/20 | 0.70 |
| ▸ | CTSK | P43235 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | CCKBR | P32239 | 6/20 | 0.59 |
| ▸ | REN | P00797 | 2/20 | 0.59 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30638853 | 0.93 | CTSL (0.71) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL31289556 | 0.91 | CTSL (0.66) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL17469419 | 0.91 | CTSL (0.66) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL30597921 | 0.91 | CTSL (0.68) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL9355924 | 0.89 | CTSL (0.74) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27871524 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27902245 | 0.89 | CTSL (0.76) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27902248 | 0.89 | CTSL (0.65) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL27902243 | 0.89 | CTSL (0.65) | CTSLCTSSCTSKMAPTTP53 | |
| SCHEMBL30976323 | 0.87 | ACE (0.77) | CTSLCTSSCTSKMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116970031-B | 2-Trp-AA-tetrahydrocarboline-3-carboxylic acid TH inhibitor and antithrombotic application thereof | 首都医科大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-116970031-A | 2-Trp-AA-tetrahydrocarboline-3-carboxylic acid TH inhibitor and antithrombotic application thereof | 首都医科大学 | 2023-10-31 | — | — | CN | disclosed |