SCHEMBL30976323

SCHEMBL30976323

CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE P12821 4/20 0.77
CTSL P07711 2/20 0.76
CTSS P25774 1/20 0.76
CTSK P43235 1/20 0.76
SCN9A Q15858 1/20 0.70
TACR1 P25103 2/20 0.70
MAPT P10636 2/20 0.68
TP53 P04637 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.66
ALOX15 P16050 1/20 0.66
SSTR3 P32745 1/20 0.63
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
ITGB2 P05107 1/20 0.62
ICAM1 P05362 1/20 0.62
ITGAL P20701 1/20 0.62
ECE1 P42892 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003555 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL29367687 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL850438 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
SCHEMBL1486167 1.00 ACE (0.77) ACECTSLCTSSCTSKSCN9A
Hydrochloric Acid SCHEMBL31472643 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
SCHEMBL30699849 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
Fluoride SCHEMBL7445962 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
Fluoride SCHEMBL7445954 0.99 ACE (0.75) ACECTSLCTSSCTSKSCN9A
SCHEMBL11403615 0.96 ACE (0.84) ACECTSLCTSSCTSKSCN9A
SCHEMBL27871524 0.96 CTSL (0.76) ACECTSLCTSSCTSKSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638415-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS Sanofi Pasteur Inc. (US) 2025-10-29 EP disclosed
WO-2024133853-A1 BIS-ESTER AND AMIDE CATIONIC LIPIDS SANOFI (FR) 2024-06-27 WO disclosed