Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424627 | 1.00 | HPGD (0.68) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL2056350 | 0.80 | LMNA (0.59) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL1684557 | 0.79 | KDM4E (0.70) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL3799234 | 0.79 | HPGD (0.60) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31324205 | 0.79 | KDM4E (0.81) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6714833 | 0.79 | LMNA (0.56) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL22728223 | 0.78 | KDM4E (0.77) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| Water SCHEMBL11335239 | 0.77 | LMNA (0.55) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL6716459 | 0.77 | KDM4E (0.52) | HPGDKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL17505205 | 0.76 | LMNA (0.54) | HPGDKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504701-A1 | BROMODOMAIN AND EXTRA-TERMINAL (BET) SUBFAMILY BROMODOMAIN 1 (BD1) SELECTIVE INHIBITORS AND METHODS USING SAME | Baylor College of Medicine (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196455-A1 | BROMODOMAIN AND EXTRA-TERMINAL (BET) SUBFAMILY BROMODOMAIN 1 (BD1) SELECTIVE INHIBITORS AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2023-10-12 | — | — | WO | disclosed |