SCHEMBL31324205

SCHEMBL31324205

Cc1ccc2[nH]c3ccc(CC(=O)O)cc3c2c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.81
▸ ALDH1A1 P00352 5/20 0.81
▸ MEN1 O00255 4/20 0.81
▸ KMT2A Q03164 4/20 0.81
▸ HPGD P15428 4/20 0.81
▸ HSD17B10 Q99714 4/20 0.81
▸ MAPT P10636 3/20 0.81
▸ GAA P10253 1/20 0.63
▸ PIM1 P11309 1/20 0.52
▸ PPARG P37231 5/20 0.51
▸ EGFR P00533 1/20 0.49
▸ KIF11 P52732 2/20 0.48
▸ PTGS1 P23219 1/20 0.47
▸ PTGS2 P35354 1/20 0.47
▸ TSHR P16473 1/20 0.46
▸ MET P08581 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ GFER P55789 1/20 0.46
▸ ACHE P22303 1/20 0.45
▸ NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29606219 0.84 KDM4E (0.60) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324202 0.83 ALDH1A1 (0.55) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324185 0.82 KDM4E (0.83) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL18938363 0.82 KDM4E (0.83) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324199 0.81 MEN1 (0.81) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324156 0.81 KDM4E (0.81) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324159 0.81 KDM4E (0.81) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL1684557 0.81 KDM4E (0.70) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL28687268 0.80 KDM4E (0.73) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL31324167 0.80 KDM4E (0.73) KDM4EALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743082-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL Business Ltd (GB) 2026-05-20 — — EP disclosed
WO-2025012634-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL BUSINESS LTD (GB) 2025-01-16 — — WO disclosed
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