Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 16/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24500766 | 1.00 | POLQ (0.59) | POLQCYP46A1PIK3CBCCNCCDK8 | |
| SCHEMBL30017462 | 0.89 | POLQ (0.62) | POLQCYP46A1 | |
| SCHEMBL29261587 | 0.89 | POLQ (0.52) | POLQCYP46A1 | |
| SCHEMBL24501111 | 0.89 | POLQ (0.62) | POLQCYP46A1 | |
| SCHEMBL27958629 | 0.84 | POLQ (0.58) | POLQ | |
| SCHEMBL24501138 | 0.83 | POLQ (0.53) | POLQPIK3CBCCNCCDK8DYRK1A | |
| SCHEMBL30640140 | 0.83 | POLQ (0.53) | POLQPIK3CBCCNCCDK8DYRK1A | |
| SCHEMBL29695035 | 0.82 | PIK3CB (0.61) | POLQPIK3CBCCNCCDK8DYRK1A | |
| SCHEMBL23542699 | 0.80 | POLQ (0.48) | POLQCYP46A1CCNCCDK8 | |
| SCHEMBL24770892 | 0.78 | POLQ (0.56) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | disclosed |