Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 14/20 | 0.58 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109275 | 0.84 | LDHA (0.57) | POLQGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL30640199 | 0.84 | POLQ (0.59) | POLQ | |
| SCHEMBL24500766 | 0.84 | POLQ (0.59) | POLQ | |
| SCHEMBL31019111 | 0.81 | POLQ (0.61) | POLQMAPTHTT | |
| SCHEMBL30017905 | 0.81 | POLQ (0.61) | POLQMAPTHTT | |
| SCHEMBL22717466 | 0.81 | POLQ (0.61) | POLQMAPTHTT | |
| SCHEMBL12121707 | 0.80 | GABRA1 (0.62) | GABRA1GABRG2GABRB3GABRA3KDM4E | |
| SCHEMBL16419694 | 0.80 | GABRA1 (0.55) | GABRA1GABRG2GABRB3GABRA3KDM4E | |
| SCHEMBL24770892 | 0.80 | POLQ (0.56) | POLQ | |
| SCHEMBL30017513 | 0.80 | POLQ (0.56) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864754-A | Five-membered azole heterocycle compound, preparation method, drug composition and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-06-18 | — | — | CN | disclosed |