Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640268 | 0.74 | MAPK14 (0.41) | KDM4EMEN1KMT2ASCN9AHSPB1 | |
| SCHEMBL15280809 | 0.69 | MEN1 (0.41) | KDM4EMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL14014291 | 0.68 | MAPK8 (0.45) | MAPK8TRPA1 | |
| SCHEMBL29536952 | 0.68 | MAPK8 (0.45) | MAPK8TRPA1MAPT | |
| SCHEMBL25226268 | 0.68 | MAPK8 (0.45) | MAPK8TRPA1MAPT | |
| SCHEMBL15180683 | 0.65 | KDM4E (0.46) | KDM4EMEN1KMT2AHSPB1ALDH1A1 | |
| SCHEMBL16838787 | 0.65 | MEN1 (0.59) | KDM4EMEN1KMT2AHSPB1GAA | |
| SCHEMBL6043168 | 0.64 | KMT2A (0.47) | CYP1A2CYP2C9CYP2C19CYP2D6KDM4E | |
| SCHEMBL1736269 | 0.63 | — | — | |
| SCHEMBL30838105 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |