Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239748 | 0.84 | MAPK14 (0.57) | MAPK14MAPK1MET | |
| SCHEMBL29537119 | 0.84 | MAPK14 (0.57) | MAPK14MAPK1MET | |
| SCHEMBL6073545 | 0.75 | HPGD (0.40) | MAPK14MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL25228119 | 0.75 | BRD4 (0.45) | MAPK14PDE4BMETALDH1A1 | |
| SCHEMBL29537130 | 0.75 | BRD4 (0.45) | MAPK14PDE4BMETALDH1A1 | |
| SCHEMBL30640323 | 0.74 | MAPK8 (0.44) | HSPB1MEN1KMT2AMAPTHTT | |
| SCHEMBL29536877 | 0.73 | HTT (0.41) | HSPB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL25225454 | 0.73 | HTT (0.41) | HSPB1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5262113 | 0.70 | MEN1 (0.39) | MEN1KMT2AMAPTRXFP1KDM4E | |
| SCHEMBL661610 | 0.69 | MEN1 (0.38) | MEN1KMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |