Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24579186 | 1.00 | CASP3 (0.47) | CASP3MDM4TP53CASP1KMT2A | |
| SCHEMBL26768402 | 0.89 | CASP3 (0.49) | CASP3MDM4TP53CASP1KMT2A | |
| SCHEMBL29400275 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL30826385 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL119369 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL30641530 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL29398340 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL10187049 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL30802532 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 | |
| SCHEMBL8037759 | 0.88 | CASP3 (0.53) | CASP3MDM4TP53CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124517-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-18 | — | — | US | disclosed |
| EP-4269422-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124517-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | VIP, NPEPPS, ANPEP | CASP3 3884/4885MDM4 2608/4885TP53 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.