Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.70 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132943 | 1.00 | DRD4 (0.70) | DRD4DRD2DRD3HTR1ASIGMAR1 | |
| SCHEMBL2660374 | 0.92 | DRD4 (0.72) | DRD4DRD2DRD3HTR1ASIGMAR1 | |
| SCHEMBL20272187 | 0.87 | MAPT (0.63) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20272185 | 0.87 | MAPT (0.58) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL16760957 | 0.87 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1 | |
| SCHEMBL10861239 | 0.85 | HTR1A (0.72) | DRD2HTR1ASIGMAR1ALDH1A1MAPT | |
| SCHEMBL20272705 | 0.83 | HTR1A (0.62) | DRD4HTR1ASIGMAR1KDM4EALDH1A1 | |
| SCHEMBL6031812 | 0.83 | DRD4 (1.00) | DRD4DRD2DRD3HTR1ASIGMAR1 | |
| SCHEMBL7498974 | 0.83 | DRD4 (0.72) | DRD4DRD2DRD3HTR1A | |
| SCHEMBL654308 | 0.82 | DRD4 (0.77) | DRD4DRD2DRD3SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285485-A | Bis-sulfonamide derivative and preparation method and application thereof | 复旦大学 | 2023-12-26 | — | — | CN | disclosed |