Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | MTOR | P42345 | 8/20 | 0.40 |
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641311 | 1.00 | PIK3CA (0.40) | PIK3CAMTORTRPC6HRH3HRH4 | |
| SCHEMBL31607811 | 0.81 | TRPC6 (0.39) | PIK3CAMTORTRPC6HRH3CHRNB2 | |
| SCHEMBL26641428 | 0.81 | TRPC6 (0.39) | PIK3CAMTORTRPC6HRH3CHRNB2 | |
| SCHEMBL31607836 | 0.79 | MAPT (0.59) | HRH3CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26641231 | 0.79 | MAPT (0.59) | HRH3CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2822118 | 0.79 | PIK3CA (0.53) | PIK3CAMTORTRPC6HRH3CHRNB2 | |
| SCHEMBL23509368 | 0.77 | SLC6A2 (0.43) | HRH3HRH4 | |
| SCHEMBL21245620 | 0.77 | PIK3CA (0.51) | PIK3CAMTORTRPC6CHRNB2CHRNA4 | |
| SCHEMBL30664069 | 0.77 | PIK3CA (0.51) | PIK3CAMTORTRPC6CHRNB2CHRNA4 | |
| SCHEMBL23634070 | 0.77 | PIK3CA (0.43) | PIK3CAMTORTRPC6HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |