Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607811 | 1.00 | TRPC6 (0.39) | TRPC6PIK3CAMTORDPP4DPP8 | |
| SCHEMBL30723925 | 0.84 | CHRNB2 (0.53) | DPP4DPP8DPP9DPP7CHRNB2 | |
| SCHEMBL27042090 | 0.83 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL23089627 | 0.82 | PIK3CA (0.41) | TRPC6PIK3CAMTORDPP4DPP8 | |
| SCHEMBL29814607 | 0.82 | PIK3CA (0.41) | TRPC6PIK3CAMTORDPP4DPP8 | |
| SCHEMBL23089626 | 0.82 | PIK3CA (0.41) | TRPC6PIK3CAMTORDPP4DPP8 | |
| SCHEMBL25558878 | 0.81 | DPP4 (0.41) | TRPC6PIK3CAMTORDPP4DPP8 | |
| SCHEMBL2822118 | 0.81 | PIK3CA (0.53) | TRPC6PIK3CAMTORCHRNB2CHRNA4 | |
| SCHEMBL30643552 | 0.81 | PIK3CA (0.40) | TRPC6PIK3CAMTORCHRNB2CHRNA4 | |
| SCHEMBL26641311 | 0.81 | PIK3CA (0.40) | TRPC6PIK3CAMTORCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |