Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.68 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | HTR1D | P28221 | 2/20 | 0.59 |
| ▸ | HTR1B | P28222 | 2/20 | 0.59 |
| ▸ | HTR1F | P30939 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260867 | 1.00 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL30096985 | 0.86 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL505125 | 0.86 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3610149 | 0.83 | HTR6 (0.51) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5746143 | 0.81 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL4019658 | 0.81 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL30229336 | 0.81 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL29686864 | 0.81 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL20843619 | 0.81 | HTR6 (0.68) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL5758119 | 0.81 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003770-A | Fused pyrimidine compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 南京师范大学 | 2023-11-07 | — | — | CN | disclosed |